Tuesday, January 31, 2012

What Happens to the Kids When Charter Schools Fail? (Time.com)

Terri Griffin made herself a promise when her youngest daughter was ready for kindergarten: the little girl would never set foot in an Akron public school. Griffin, an Akron jewelry store clerk who is a graduate of the Ohio city's school system, had sent eight children -- two of her own and six others she raised as her own -- to traditional public schools.

She felt they were pushed through to a diploma and didn't learn enough. Teachers were eager to recommend special education, but Griffin couldn't get them to provide other basic extra help. Two years ago when her youngest daughter was entering kindergarten, she sought out a charter school, Lighthouse Academy, and hoped for a better outcome. (MORE: New Grades On Charter Schools)

Griffin didn't know about the Lighthouse Academy's low test scores or that it had been identified by the state as being in an academic emergency on and off since opening in 2000. Instead, when she visited the West Akron school, Griffin saw caring teachers working with small classes in a school that was well established in the community. She hasn't once regretted her decision.

Now, under Ohio's charter school closure law, considered the toughest in the nation, Lighthouse Academy is slated to be closed at the end of the year. The 2006 law mandates that any charter school that has received the state's Academic Emergency rating or been placed on academic watch for two out of three years will be shut down. (The ratings are based on state test scores.)

Most of Lighthouse's 66 students will be thrust back into the same public schools their parents tried to flee. Nearby public schools only perform slightly better than Lighthouse on standardized tests, and some do just as poorly.

The closure is another blow for the children of this fading industrial city, where a third of all children live in poverty and about a quarter of high schoolers fail to graduate. It's a scenario becoming familiar to thousands of families in the nation's poorest neighborhoods as more and more districts start cracking down on low-performing charter schools, which get public funds but operate without the usual bureaucratic constraints. (PHOTOS: A Mandarin School in Minneapolis)

The dismantling of so many charters has some experts worrying that when students are forced to leave educational environments where they have friends and feel comfortable, the disruption is destabilizing and upsetting to some of the system's most vulnerable populations. Robert Slavin, director of the Center for Research and Reform in Education at Johns Hopkins University in Maryland, believes closure should be a last resort, after giving schools support and experimenting with solutions. Otherwise, well-meaning educational programs could wind up hurting the very kids they are trying to help. "Letting alone or closing are not the only two options," Slavin said. Closing "is very damaging to kids."

Nonetheless, the crack down on ineffective charter schools has the backing of charter supporters as well as critics. In an effort to save the charter movement, which has come under increasing scrutiny, advocates have asked for more accountability, supporting forced closures of low-performing schools. Florida has already adopted a law similar to Ohio's. During the current legislative session, charter advocates in Missouri are pushing a bill that would require charter schools to set up specific benchmarks, giving sponsors an easy way to hold schools accountable. The California Charter Schools Association has said it will start urging school boards not to allow faltering schools to stay open. (MORE: Why It's Time to Replace No Child Left Behind)

Bill Sims, president of the Ohio Alliance of Public Charter Schools, says he regularly gets calls from his counterparts in other states asking for more information on Ohio's law so they can use it as a model for their own legislation.

"The good news is Ohio doesn't keep underperforming schools open. The bad news is it hit Lighthouse," said Marianne Cooper, director of the Richland Academy of the Arts, the non-profit community arts center in Mansfield, Ohio that sponsors Lighthouse. The organization has closed the four other charters it operated, but saw potential in Lighthouse because of some of the very same things that attracted and have impressed Griffin.

"I love the way the classes are structured," Griffin said, of her now-second-grader's experience. "The teachers that she has had take those children in as their own."

The personal attention has not translated into convincing data, however. Lighthouse has struggled on state tests since it opened, falling well below state and district averages. Over the past six years, an average of only 31 percent of its students annually reached proficiency across all grades and subjects. In some cases, only one student per class passed the exam.

Last year, every student demonstrated at least one year's worth of growth, according to state standardized tests, although many remained below grade level in their performance.

Using this as a key argument, Principal Fannie Brown plans to appeal the closure decision. However, the Ohio Department of Education said the decision to close would not be overturned.

"While the school made some academic gains in the last report card period, it was simply not enough to surmount the consequences of the closure law," said Ohio Education Department spokesman Patrick Gallaway.

MORE: New Grades on Charter Schools

If Lighthouse closes, as expected, it could represent the beginning of a major change in the way charter schools operate. Nationally, charter schools with low scores are only slightly more likely to close than traditional schools with low scores, according to a recent study by the Fordham Institute that examined charters in 10 different states. New data released by the Center for Education Reform indicates that 15 percent of charter schools have been shut down over the course of the charter movement, which began two decades ago. But fewer than 200 of the 6,700 charters that have opened since 1992 were closed down for academic reasons; the majority were shuttered due to financial or mismanagement problems.

Jeanne Allen, president of the center, a pro-charter group, says that administrative problems indicate that a school isn't working long before test scores come out; the center's data, she says, shows that failing schools do get shut down even without the new regulations. "The vast majority succeed [and] stay open," she said. "Those that don't are closed within a few short years before they can ever have any negative impact on students."

Many others within the charter movement, though, are not so convinced that closures are always so timely.

In California, for instance, the charter school association is poised to start holding charters to task with or without a new law, and is urging school boards not to allow faltering schools to stay open. Doing so might encourage more school boards to take the politically unpopular step of closing down schools, the group says. Myrna Castrej?n, a senior vice-president of the California Charter Schools Association, said her group couldn't keep making the case for charter schools if it was seen as soft on failing charters.

More than almost any other state, Ohio shows that change is possible. The state originally took the "let a thousand flowers bloom" approach, encouraging rapid expansion of charter schools with minimal oversight. Ohio educators expected that parents would stay away from bad charters, which would then be forced to close down, said Todd Ziebarth, vice president for state advocacy and support for the National Alliance for Public Charter Schools.(MORE: Grading the GOP Candidates on Education)

Instead, the state became something of a national embarrassment in the charter movement, with headlines about gross mismanagement and financial scandals. In 2006, when the automatic closure law was written, more than half of Ohio's charter schools were rated a D or F under the state grading system.

The new regulation is a big step forward, but it hasn't fixed everything. Only 17 charters have been shut down in the past five years as a result of the new law, in part because of a loophole that allows high schools with "dropout prevention programs" to stay open regardless of performance. And more charters have opened to replace those that have been shut down.

Ziebarth thinks closing schools like Lighthouse should be an easy decision. If a school fails to live up to expectations in five years, it should be shut down, he said: "What we can't do is perpetuate mediocrity and failure."

Nonetheless, Lighthouse Principal Fannie Brown and her faculty members think they should have more time to improve before putting their kids through the disruption of being sent back to regular public schools, some of which might be worse or only slightly better than Lighthouse. They admit that the school has had a rocky history but say they've completely replaced the staff in an ongoing effort to improve. "I only wish that Dr. Brown had taken this school on two or three years ago," Cooper said.(LIST: 7 Things You Need to Know About a School (Before You Enroll Your Kid)

For now, it's business as usual for Lighthouse students. On a cold November afternoon, first- and second-graders practiced how to take out books and put them back with the spine facing the right way in the school's brand new library, then danced to a YouTube video of "Five Little Reindeer Jumping in the Snow."

But the adults in the building can't escape the sadness of impending closure.

Over microwaved frozen pizza and reheated leftovers in the staff lounge, teachers say they're just trying to get through the school year before thinking about looking for other jobs. They worry about what will happen to their children next year in "bigger, rougher" public schools. "The best schools in Akron," said teacher Jessica Satterlee, "are not where our kids live."

Terri Griffin is still hoping that the closing can be averted, but if not, she's sticking to her vow. If Lighthouse shuts down, her daughter still won't be going to the Akron Public Schools. Instead, she will be in private school, which Griffin's extended family will help pay for. "It's hard to explain -- as a mother who really, really has a passion for their child's education -- I felt so bad. I didn't know what to do," Griffin said. "This school is the only thing she knows."

With additional reporting by Emily Alpert in California

This story was produced by The Hechinger Report, a nonprofit, nonpartisan education-news outlet affiliated with Teachers College, Columbia University.

PHOTOS: A Separate Peace: Portraits from a Gay-Friendly School

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Source: http://us.rd.yahoo.com/dailynews/rss/education/*http%3A//news.yahoo.com/s/time/20120131/us_time/08599210573300

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Gingrich makes play for evangelicals, tea partiers

Republican presidential candidate, former House Speaker Newt Gingrich, speaks to media during a news conference outside the Exciting Idlewild Baptist Church, Sunday, Jan. 29, 2012, in Lutz, Fla. (AP Photo/Matt Rourke)

Republican presidential candidate, former House Speaker Newt Gingrich, speaks to media during a news conference outside the Exciting Idlewild Baptist Church, Sunday, Jan. 29, 2012, in Lutz, Fla. (AP Photo/Matt Rourke)

Republican presidential candidate, former House Speaker Newt Gingrich, with his wife Callista, campaign at The Villages, Sunday, Jan. 29, 2012, in Lady Lake, Fla. (AP Photo/Matt Rourke)

Republican presidential candidate, former House Speaker Newt Gingrich, meets with supporters during a campaign event at the The Villages, Sunday, Jan. 29, 2012, in Lady Lake, Fla. (AP Photo/Matt Rourke)

(AP) ? Facing the possibility of a stinging defeat, Republican presidential contender Newt Gingrich combined sharp attacks on Mitt Romney with unspoken appeals for support among the state's evangelicals on Sunday, two days before the pivotal Florida primary.

In an unusual commitment of campaign time, the former House speaker attended a pair of Baptist worship services, where he sat in a pew, accompanied by his wife, Callista, and made no remarks.

In between a morning stop at a megachurch in the Tampa area and an evening visit to a church in Jacksonville, Gingrich unleashed an attack on Romney as a "pro-abortion, pro-gun control, pro-tax increase liberal" who could not be trusted to bring conservative values to the White House.

He also drew rousing cheers from a large crowd, numbered in the thousands, at a retirement community, where a Tea Party Express bus rolled slowly behind the platform where he was speaking.

Increasingly, Gingrich has reached out to evangelicals and tea party advocates as the Florida primary approaches, touting an endorsement from campaign dropout Herman Cain as well as former Alaska Gov. Sarah Palin's recent accusation that the establishment was trying to "crucify" him.

Standing outside the First Jacksonville Baptist church as dusk fell, Kurt Kelly, chairman of Florida Faith Leaders for Newt Gingrich, said the candidate held a midweek conference call with an estimated 1,000 evangelical pastors around the state.

He said the goal of the call was to solidify support as much as possible behind Gingrich, at the expense of rival contender Rick Santorum, who is running a poor third in the pre-primary polls in the state.

In the course of the conversation, Kelly said, Gingrich "shared his faith, shared his vision and shared his past."

Kelly did not expand on his reference to Gingrich's past, although the former speaker has been married three times.

He said one of the other pastors on the call questioned Gingrich further, and the candidate "showed a contrite heart and showed true confession and true repentance."

Gingrich was anything but repentant in his remarks about Romney during the day.

During a pair of Sunday morning television interviews, he said his chief rival had adopted a "basic policy of carpet-bombing his opponent."

One of the ads being run by Romney suggests that Gingrich is exaggerating his ties to Ronald Reagan. Gingrich chafed at that, noting that the former president's son Michael was joining him on the campaign trail Monday "to prove to everybody that I am the heir to the Reagan movement, not some liberal from Massachusetts."

Cain, a tea party favorite, will also appear with Gingrich on Monday.

At a large rally Sunday at The Villages, a sprawling retirement community in central Florida, Gingrich accused Democratic President Barack Obama of coddling foreign leaders like Venezuela's Hugo Chavez and Iran's Mahmoud Ahmadinejad.

"I believe we need to be stronger than our potential enemies," Gingrich told the crowd. "The president lives in a fantasy world where there are no enemies, there are just misguided people with whom he has not yet had coffee."

He said Chavez "deliberately, cynically and insultingly gave him an anti-American book and Obama didn't have a clue that he'd been insulted."

He said the Obama administration should be focused on Ahmadinejad's "pledge to wipe out Israel and drive America out of the Middle East."

"But if I were a left-wing Harvard law graduate surrounded by really clever left-wing academics I would know that this was really a sign that (Ahmadinejad) probably had a bad childhood," Gingrich said.

He described Obama's approach to Ahmadinejad as, "If only we could unblock him we could be closer to him and we could be friends together."

Gingrich, who served in the House for two decades, also made a populist pitch as a Washington outsider. He said the GOP's "old establishment" is trying to block his path to nomination.

"It's time that someone stood up for hard-working, taxpaying Americans and said, 'Enough,'" Gingrich said. "And if that makes the old order uncomfortable, my answer is, 'Good.'"

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2012-01-29-Gingrich/id-e5ff832d294b489d9925ee7cf3351f41

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Monday, January 30, 2012

Spider-silk skin stops a speeding bullet

Caitlin Stier, video intern

What if your skin could resist a speeding bullet? Now a new futuristic tissue designed by artist Jalila Essa?di, which reinforces human skin cells with spider silk, can stop a whizzing projectile without being pierced. Although its threads may look fragile, a spider-silk weave is four times stronger than Kevlar, the material used in bulletproof vests.

In the first clip, the bioengineered skin cushions a bullet fired at half speed. But its resistance has its limits: when shot at a full speed of 329 m/s, the bullet pierces the material and travels through it. The same tests were also performed with piglet skin, human skin and human skin fused with regular silkworm silk, which were all penetrated by bullets of both speeds.

An international team worked together to create the new material. First, transgenic goats and silkworms equipped to produce spider-silk proteins spun out the raw material at the synthetic biology lab at Utah State University. The cocoons were then shipped to South Korea, where they were reeled into thread, before being woven into fabric in Germany. The modified silk was then wedged between bioengineered skin cells developed by biochemist Abdoelwaheb El Ghalbzouri at the Leiden University Medical Center in the Netherlands. After five weeks of incubation, the hybrid skin was ready for target practice.

In addition to exploring the material artistically, Essa?di is also looking into practical uses, such as skin transplants. Spider silk is already being developed by other teams for high-tech applications, which range from artificial corneas to brain implants.

For more about spider silk spin-offs, check out our full-length feature: "Stretching spider silk to its high-tech limits". Or you might also like to find out about the science behind a lavish golden spider-silk cape, currently on display at the Victoria and Albert Museum in London.

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Michael Lohan Back in the Hospital With Chest Pains


Lindsay Lohan's estranged and equally troubled father Michael Lohan was taken back to the hospital early Friday morning after experiencing chest pains.

MiLo was transferred from a rehab facility in Palm Beach, Fla., after doctors found blood clots and put him on medication to try and break them up.

Doctors feel they don't need to perform surgery, but they want to keep in the hospital for a couple of days to make sure Mike's medication works.

Fist-Pumpin' MiLo!

This is the second time in less than two months Lohan has been hospitalized for recurring heart problems. He collapsed at an AA meeting the last time.

He had surgery to repair a blockage back on December 5.

Lohan is due to be released from rehab on March 16. It's unclear whether that will be pushed back due to this and previous hospital stays.

We wish him a fast recovery in any case.

Source: http://www.thehollywoodgossip.com/2012/01/michael-lohan-back-in-the-hospital-with-chest-pains/

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Sunday, January 29, 2012

High School Graduation: 'How I Went From Slacker to Star Student'

This is a teen-written article from our friends at Youth Communication, a nonprofit organization that helps marginalized youth develop their full potential through reading and writing.

Names have been changed.

?Yo, do you understand what we have to do? ?Cause I damn sure don?t,? I whispered to a friend one day during math class. We were supposed to be working on a sheet of problems, but neither of us understood how to do it. I raised my hand, and when the teacher came over, I told him I was confused.

?Well, Miss, you should have been paying attention when I was giving the lesson and not so focused on talking to your friend.?

?But Mr. Cooper, I need help. I don?t get it. Are you going to help me or not?? I asked, getting angry.

?No, I?m not going to re-teach it to you when you should have been paying attention,? he replied. I was so mad I didn?t do any of his work for the rest of class.

What pissed me off the most was the way he talked to me. He should have sat down with me and broken down the problem. I decided to stop going to his class. Why should I waste my time with a teacher who won?t teach me?

Throughout elementary and middle school, I had been a relatively good student. In fact, math?Mr. Cooper?s subject?had always been my favorite class. But high school was different.

A New Routine

This was the first time I?d gone to a school outside of Brooklyn, and everything seemed really impersonal. Murry Bergtraum High School was a five-story brick building in downtown Manhattan with thousands of students. It was so big that my daily routine included walking around in a circle, looking for my classes. I felt uncomfortable and unsafe in such a big school with its huge population of students.

The teachers? attitudes affected how I felt about school, too. Most of them never bothered to learn my first name, which says a lot to me. They also seemed less supportive of students than the teachers in my previous schools.

After a while my attitude toward school and the teachers was ?Screw them.? I felt like I was wasting my time trying to learn if they weren?t going to help me, so I started cutting my least favorite classes. A month after my first cutting experience, it had become a part of my regular routine.

A normal day went like this: I?d walk into the building and check the time on my phone. It would be a little after 11 a.m., which meant I was a full two hours late to school. Acting nonchalant, I continued on to class. Business law and English were the only classes that I actually liked. The teachers were helpful, and I respected and loved them. But I only stayed around for those classes.

After I?d bumped into a few friends and discussed our afternoon plans, we?d all decide that we were going to leave school. Usually, we ended up in Burger King, Mickey D?s, or Wendy?s, but if we wanted to just relax, we would walk through a couple of stores or go kick back by the seaport.

When I was cutting I wasn?t thinking about much. All I knew was that I didn?t like my classes, I didn?t like my teachers, and I didn?t want to be there. I wasn?t thinking about my future at all, because I felt like I didn?t have much of a future to look forward to.

A Million and Two Steps Behind

The cutting went on for almost two years before it really caught up with me. Going into my junior year at Bergtraum, I was supposed to have earned at least 33 credits, but I only had five. I was still considered a freshman and at the rate I was going, I?d never graduate.

When I realized that, I felt overwhelmed. It hurt to hear my friends talk about how they?d made it to the next grade officially, and I was still a million and two steps behind. I considered dropping out because I felt hopeless, like an underachiever. Even so, I knew deep in my heart that I was capable of succeeding; I just didn?t know exactly how to go about it.

I knew I needed a change. I wasn?t getting anywhere in that school, so I decided to transfer to a new one. I was told that there were alternative schools that are smaller than your average high school, with a capacity of roughly 150 students. That sounded good, plus, I heard that the teachers at these smaller schools are dedicated, devoted, and actually give you one-on-one help. I decided to transfer to one of these alternative schools, South Brooklyn Community High School, that happened to be extremely close to my home. There was just one catch: they had to accept me.

During the interview, I sat in a small office with my mom while one of the school counselors asked some basic questions: Why are you here? What didn?t you like about your old school? Then, after asking my mother to leave the room, the counselor started asking me about my entire personal history. He wanted to know the ins and outs of my relationship with my mother and my father, whether anyone else was living in my household besides my mother and me, and lots of other personal stuff.

It felt like he was interrogating me, like I was a criminal about to be taken off to jail. It seemed unnecessary?how would all that information determine whether or not I should be accepted? I think my defensiveness came through in my answers.

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Source: http://www.huffingtonpost.com/2012/01/29/from-slacker-to-star-stud_n_1239763.html

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Saturday, January 28, 2012

Notion in Motion: Wireless Sensors Monitor Brain-Waves on the Fly

eeg, brain, interface, game"TIP OF THE ICEBERG": NeuroSky, Inc.'s brain-computer interface shown here just scratches the surface of what is possible thanks to advances in mobile electroencephalographic (EEG) brain-wave detection technology, says University of California, San Diego's Scott Makeig. Image: Courtesy of Neurosky, Inc.

A fighter pilot heads back to base after a long mission, feeling spent. A warning light flashes on the control panel. Has she noticed? If so, is she focused enough to fix the problem?

Thanks to current advances in electroencephalographic (EEG) brain-wave detection technology, military commanders may not have to guess the answers to these questions much longer. They could soon be monitoring her mental state via helmet sensors, looking for signs she is concentrating on her flying and reacting to the warning light.

This is possible because of two key advances made EEG technology wireless and mobile, says Scott Makeig, director of the University of California, San Diego's Swartz Center for Computational Neuroscience (SCCN) in La Jolla, Calif. EEG used to require users to sit motionless, weighted down by heavy wires. Movement interfered with the signals, so that even an eyebrow twitch could garble the brain impulses.

Modern technology lightened the load and wirelessly linked the sensors and the computers that collect the data. In addition, Makeig and others developed better algorithms?in particular, independent component analysis. By reading signals from several electrodes, they can infer where, within the skull, a particular impulse originated. This is akin to listening to a single speaker's voice in a crowded room. In so doing, they are also able to filter out movements?not just eyebrow twitches, but also the muscle flexing needed to walk, talk or fly a plane.

EEG's most public face may be two Star Wars?inspired toys, Mattel's Mindflex and Uncle Milton's Force Trainer. Introduced in 2009, they let wannabe Jedi knights practice telekinesis while wearing an EEG headset. But these toys are just the "tip of the iceberg," says Makeig, whose work includes mental concentration monitoring. "Did you push the red button and then say, 'Oops!' to yourself? It would be useful in many situations?including military?for the system to be aware of that."

That kind of "mental gas gauge" is just one of many projects Makeig is running at the SCCN, which is part of U.C. San Diego's Institute for Neural Computation (INC). He also combines mobile EEG with motion-capture technology, suiting volunteers in EEG caps and LED-speckled spandex suits so he can follow their movements with cameras in a converted basement classroom. For the first time, researchers like Makeig can examine the thoughts that lead to movement, in both healthy people and participants with conditions such as autism. Makeig calls the system Mobile Brain/Body Imaging, or MoBI. It allows him to study actions "at the speed of thought itself," he says.

EEG does not directly read thoughts. Instead, it picks up on the electrical fields generated by nerves, which communicate via electricity. The EEG sensors?from the one on the Star Wars games to the 256 in Makeig's MoBI?are like microphones listening to those microvolt-strength neural signals, says Tansy Brook, head of communications for NeuroSky Brain?Computer Interface Technology in San Jose, Calif., makers of the chip in the Star Wars toys and many other research, educational and entertainment products.

For one project, Makeig is collaborating with neuroscientists Marissa Westerfield and Jean Thompson, U.C. San Diego researchers studying movement behavior in teenagers with autism. They put the teens, wearing the EEG sensors and LEDs, in Makeig's special classroom. Then, they project a spaceship on the walls. The kids have to chase the spaceship as it darts from one point to another. Although the results are not yet in, Westerfield suspects that people with autism, compared with those who are non-autistic, will take longer to process where the spaceship has gone and readjust their movements toward it. "If we had a better idea of the underlying deficits?then we could possibly design better interventions," such as targeted physical therapy for the movement problems autistic people have, Westerfield says.

Neuroscientists and psychologists have been using EEG to eavesdrop on brain waves since 1926, and doctors employ it to study sleep patterns and observe epileptic seizures. During most of that time, subjects had to sit in an electrically shielded booth, "like a big refrigerator," says John Foxe, a neuroscientist at Albert Einstein College of Medicine in New York City. He calls Makeig's MoBI "technical wizardry" that will enable scientists "to watch the brain and how it works in much more realistic settings."

Wireless EEG has already had an impact on gaming. San Francisco?based Emotiv has since 2009 sold its EPOC EEG headset, which uses electrical signals to determine a player's emotional state?excitement, frustration and boredom each create a different pattern. Gamers using Emotiv's technology can also create mental "spells" to lift or push virtual objects, says Geoff Mackellar, CEO of Emotiv?s research unit based in Sydney, Australia. The EPOC is also regularly used in research labs and may have medical applications in the future, Mackellar adds.

Wireless EEG technology provides signals as clear as the wired version, Makeig says, and at about 3.5 kilograms his machinery is "luggable." (Emotiv's and NeuroSky's headsets, which use fewer electrodes, are lighter.) "Of course, we're not starting with ballet dancers doing The Rite of Spring," he admits, but the team has succeeded with joggers on a treadmill. One challenge they would still like to overcome is to remove the sticky, conductive gel that goes under each electrode. It can certainly be done?Emotiv's electrodes use only saltwater and NeuroSky's are dry.

Tzyy-Ping Jung, associate director of the SCCN, predicts the group will make a dry, 64-electrode system within a couple of years. He and Makeig envision the headset will help paralyzed people interact with the world, warn migraine sufferers of an impending headache, and adjust computerized learning to match a student's personal pace, among other potential applications.

"It's certainly something that everyone can have at home," Emotiv's Mackellar says.

Source: http://rss.sciam.com/click.phdo?i=60da3ae60f492ca5c90e0ebaa19105e9

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Friend says on 911 call Demi Moore was convulsing (AP)

LOS ANGELES ? Demi Moore smoked something before she was rushed to the hospital on Monday night and was convulsing and "semi-conscious, barely," according to a caller on a frantic 911 recording released Friday by Los Angeles fire officials.

The woman tells emergency operators that Moore, 49, had been "having issues lately."

"Is she breathing normal?" the operator asks.

"No, not so normal. More kind of shaking, convulsing, burning up," the friend says as she hurries to Moore's side, on the edge of panic.

The recording captures the 10 minutes it took paramedics to arrive as friends gather around the collapsed star and try to comfort her as she trembles and shakes.

Another woman is next to Moore as the dispatcher asks if she's responsive.

"Demi, can you hear me?" she asks. "Yes, she's squeezing hands. ... She can't speak."

When the operator asks what Moore ingested or smoked, the friend replies, but the answer was redacted.

"Some form of ... and then she smoked something. I didn't really see. She's been having some issues lately with some other stuff. So I don't know what she's been taking or not," the friend says.

The city attorney's office advised the fire department to redact details about medical conditions and substances to comply with federal medical privacy rules.

"She smoked something. It's not marijuana. It's similar to incense," the friend says to the 911 operator.

While Moore's friends don't say exactly what she smoked, an increasingly popular drug known as Spice is sometimes labeled as "herbal incense."

Spice is a synthetic cannabis drug and also called K2. It's sold in small packets over the Internet, in smoke shops and at convenience stores. The packaging sometimes reads "not for human consumption" to conceal its purpose.

In 2011, there were twice as many spice-related calls to Poison Control Centers nationwide as in the previous year, according to the National Office of Drug Control Policy.

The adverse health effects associated with synthetic marijuana include anxiety, vomiting, racing heartbeat, seizures, hallucinations, and paranoid behavior.

Asked if Moore took the substance intentionally or not, the woman says Moore ingested it on purpose but the reaction was accidental.

"Whatever she took, make sure you have it out for the paramedics," the operator says.

The operator asks the friend if this has happened before.

"I don't know," she says. "There's been some stuff recently that we're all just finding out."

Moore's publicist, Carrie Gordon, said previously that the actress sought professional help to treat her exhaustion and improve her health. She would not comment further on the emergency call or provide details about the nature or location of Moore's treatment.

The past few months have been rocky for Moore.

She released a statement in November announcing she had decided to end her marriage to fellow actor Ashton Kutcher, 33, following news of alleged infidelity. The two were known to publicly share their affection for one another via Twitter.

Moore still has a Twitter account under the name mrskutcher but has not posted any messages since Jan. 7.

During the call, the woman caller says the group of friends had turned Moore's head to the side and was holding her down. The dispatcher tells her not to hold her down but to wipe her mouth and nose and watch her closely until paramedics arrive.

"Make sure that we keep an airway open," the dispatcher says. "Even if she passes out completely, that's OK. Stay right with her."

The phone is passed around by four people, including a woman who gives directions to the gate and another who recounts details about what Moore smoked or ingested. Finally, the phone is given to a man named James, so one of the women can hold Moore's head.

There was some confusion at the beginning of the call. The emergency response was delayed by nearly two minutes as Los Angeles and Beverly Hills dispatchers sorted out which city had jurisdiction over the street where Moore lives.

As the call is transferred to Beverly Hills, the frantic woman at Moore's house raises her voice and said, "Why is an ambulance not on its way right now?"

"Ma'am, instead of arguing with me why an ambulance is not on the way, can you spell (the street name) for me?" the Beverly Hills dispatcher says.

Although the estate is located in the 90210 ZIP code above Benedict Canyon, the response was eventually handled by the Los Angeles Fire Department.

By the end of the call, Moore has improved.

"She seems to have calmed down now. She's speaking," the male caller told the operator.

Moore and Kutcher were wed in September 2005.

Kutcher became a stepfather to Moore's three daughters ? Rumer, Scout and Tallulah Belle ? from her 13-year marriage to actor Bruce Willis. Moore and Willis divorced in 2000 but remained friendly.

Moore and Kutcher created the DNA Foundation, also known as the Demi and Ashton Foundation, in 2010 to combat the organized sexual exploitation of girls around the globe. They later lent their support to the United Nations' efforts to fight human trafficking, a scourge the international organization estimates affects about 2.5 million people worldwide.

Meanwhile, Millennium Films announced Friday that Sarah Jessica Parker will replace Moore in the role of feminist Gloria Steinem in its production of "Lovelace," a biopic about the late porn star Linda Lovelace. A statement gave no reason for the change. The production, starring Amanda Seyfried, has been shooting in Los Angeles since Dec. 20.

Moore can be seen on screen in the recent films "Margin Call" and "Another Happy Day." Kutcher replaced Charlie Sheen on TV's "Two and a Half Men" and is part of the ensemble film "New Year's Eve."

Source: http://us.rd.yahoo.com/dailynews/rss/movies/*http%3A//news.yahoo.com/s/ap/20120127/ap_en_mo/us_people_demi_moore

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Friday, January 27, 2012

Google's Android developers want you to say goodbye to the menu button

Action bar

Goodbye menu button, hello Action Bar overflow!  Today on the Android Developers blog Scott Main, lead technical writer from Google, wrote up a nice piece of prose about how developers should migrate away from the traditional menu-button based way of designing applications.  You see, Ice Cream Sandwich allows for the folks designing phones to do away with all those buttons we've grown accustomed to at the bottom of our screen, and replace them with software based buttons built into the OS and apps.  It's something we first saw in Honeycomb tablets, where the need for menu buttons was removed by the introduction of the ActionBar class.  

Google wants developers, and in turn us users, to learn to love the Action Bar.  Scott gives examples of how the new Action Bar "overflow" (those three dots that replace a menu button in ICS) can replace what we traditionally needed a menu button for, and even how to build applications to use both methods -- developers don't want to forget all the devices that haven't been updated to Ice Cream Sandwich yet.  It's an interesting read for those who keep up with Android application interface guidelines, and a must-read for all you developers out there.  

Most importantly, Scott stresses that the application UI should have all the important  elements right up front for the user to see, and the overflow should be used for things not important enough to be on the screen.  He also gives instruction on how to make the legacy menu button not appear if it's not being used, and how to get rid of the whole Action Bar if an application doesn't need it.  As developers get their apps updated for ICS and beyond, we'll be able to say goodbye to those three dots we chase all over on "buttonless" phones and tablets.  That's a good thing.

Source: Android Developers Blog.  Thanks, Sebastian!



Source: http://feedproxy.google.com/~r/androidcentral/~3/JtX-pavhiJ4/story01.htm

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Making sense of sensory connections

Making sense of sensory connections [ Back to EurekAlert! ] Public release date: 26-Jan-2012
[ | E-mail | Share Share ]

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Caltech researchers identify mechanism behind associative memory by exploring insect brains

PASADENA, Calif.A key feature of human and animal brains is that they are adaptive; they are able to change their structure and function based on input from the environment and on the potential associations, or consequences, of that input. For example, if a person puts his hand in a fire and gets burned, he learns to avoid flames; the simple sight of a flame has acquired a predictive value, which in this case, is repulsive. To learn more about such neural adaptability, researchers at the California Institute of Technology (Caltech) have explored the brains of insects and identified a mechanism by which the connections in their brain change to form new and specific memories of smells.

"Although these results were obtained from experiments with insects, the components of the mechanism exist also in vertebrate, including mammalian, brains which means that what we describe may be of wide applicability," says Stijn Cassenaer, a Broad Senior Research Fellow in brain circuitry at Caltech and lead author of a paperpublished in the journal Nature on January 25that outlined the findings. The study focused on insects because their nervous systems are smaller, and thus likely to reveal their secrets sooner than those of their vertebrate counterparts.

To home in on sensory memories, the researchers concentrated on olfaction, or the sense of smell. When a person encounters a favorite food or the perfume of a loved one, she will typically experience a recall, usually positive, based on the memories evoked by those smells. Such a recallto a smell, sound, taste, or any other sensory stimulusis evidence of "associative" learning, says Gilles Laurent, a former professor of biology at Caltech and senior author of the study, as learning often means assigning a value, such as beneficial or not, to inputs that were until then neutral. The original, neutral stimulus acquires significance as a result of being paired, or associated, with a reinforcing reward or punishmentin this case, the pleasant emotion recalled by a smell.

"When we learn that a particular sensory stimulus predicts a reward, there is general agreement that this knowledge is stored by changing the connections between particular neurons," explains Cassenaer. The problem, however, is that the biological signals that represent value (positive or negative) are broadcast nonspecifically throughout the brain. How then, are they assigned specifically to particular connections, so that a certain sensory input, until then neutral, acquires its new, predictive value? "In this study, we carried out experiments to investigate how the brain identifies exactly which connections, out of an enormously large number of possibilities, should be changed to store the memory of a specific association."

To get a closer look at these connections, Cassenaer and Laurentwho is now director at the Max Planck Institute for Brain Research in Germanymeasured neural activity in an area of the locust brain where olfactory memories are thought to be stored. They found that what allows the brain to identify which synapses should be modified, and thus where the nonspecific reward signal should act, is a very transient synchronization between pairs of connected neurons.

"When pairs of connected neurons fire in quick succession, the strength of their connection can be altered. This phenomenon, called spike-timing dependent plasticity, has been known for many years. What is new, however, is recognizing that it also makes these connections sensitive to an internal signal released in response to a reward," says Cassenaer. "If no reward is encountered, the cells' sensitivity fades. However, if the sensory stimulus is followed by a reward within a certain time window, then these connections are the only ones altered by the internal reward signal. All other connections remain unaffected."

Laurent says that the molecular underpinnings of this phenomenon, as well as the process by which the stored memories are later read out, are an area of much-needed exploration.

"We are currently developing the necessary tools to examine this with sufficient specificity, which will allow us to evaluate animals' behavior as they learn," says Cassenaer.

###

The study, "Conditional modulation of spike-timing-dependent plasticity for olfactory learning," was funded by the Lawrence Hanson Chair at Caltech, the National Institutes on Deafness and other Communication Disorders, Caltech's Broad Fellows Program, the Office of Naval Research, and the Max Planck Society.


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Making sense of sensory connections [ Back to EurekAlert! ] Public release date: 26-Jan-2012
[ | E-mail | Share Share ]

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Caltech researchers identify mechanism behind associative memory by exploring insect brains

PASADENA, Calif.A key feature of human and animal brains is that they are adaptive; they are able to change their structure and function based on input from the environment and on the potential associations, or consequences, of that input. For example, if a person puts his hand in a fire and gets burned, he learns to avoid flames; the simple sight of a flame has acquired a predictive value, which in this case, is repulsive. To learn more about such neural adaptability, researchers at the California Institute of Technology (Caltech) have explored the brains of insects and identified a mechanism by which the connections in their brain change to form new and specific memories of smells.

"Although these results were obtained from experiments with insects, the components of the mechanism exist also in vertebrate, including mammalian, brains which means that what we describe may be of wide applicability," says Stijn Cassenaer, a Broad Senior Research Fellow in brain circuitry at Caltech and lead author of a paperpublished in the journal Nature on January 25that outlined the findings. The study focused on insects because their nervous systems are smaller, and thus likely to reveal their secrets sooner than those of their vertebrate counterparts.

To home in on sensory memories, the researchers concentrated on olfaction, or the sense of smell. When a person encounters a favorite food or the perfume of a loved one, she will typically experience a recall, usually positive, based on the memories evoked by those smells. Such a recallto a smell, sound, taste, or any other sensory stimulusis evidence of "associative" learning, says Gilles Laurent, a former professor of biology at Caltech and senior author of the study, as learning often means assigning a value, such as beneficial or not, to inputs that were until then neutral. The original, neutral stimulus acquires significance as a result of being paired, or associated, with a reinforcing reward or punishmentin this case, the pleasant emotion recalled by a smell.

"When we learn that a particular sensory stimulus predicts a reward, there is general agreement that this knowledge is stored by changing the connections between particular neurons," explains Cassenaer. The problem, however, is that the biological signals that represent value (positive or negative) are broadcast nonspecifically throughout the brain. How then, are they assigned specifically to particular connections, so that a certain sensory input, until then neutral, acquires its new, predictive value? "In this study, we carried out experiments to investigate how the brain identifies exactly which connections, out of an enormously large number of possibilities, should be changed to store the memory of a specific association."

To get a closer look at these connections, Cassenaer and Laurentwho is now director at the Max Planck Institute for Brain Research in Germanymeasured neural activity in an area of the locust brain where olfactory memories are thought to be stored. They found that what allows the brain to identify which synapses should be modified, and thus where the nonspecific reward signal should act, is a very transient synchronization between pairs of connected neurons.

"When pairs of connected neurons fire in quick succession, the strength of their connection can be altered. This phenomenon, called spike-timing dependent plasticity, has been known for many years. What is new, however, is recognizing that it also makes these connections sensitive to an internal signal released in response to a reward," says Cassenaer. "If no reward is encountered, the cells' sensitivity fades. However, if the sensory stimulus is followed by a reward within a certain time window, then these connections are the only ones altered by the internal reward signal. All other connections remain unaffected."

Laurent says that the molecular underpinnings of this phenomenon, as well as the process by which the stored memories are later read out, are an area of much-needed exploration.

"We are currently developing the necessary tools to examine this with sufficient specificity, which will allow us to evaluate animals' behavior as they learn," says Cassenaer.

###

The study, "Conditional modulation of spike-timing-dependent plasticity for olfactory learning," was funded by the Lawrence Hanson Chair at Caltech, the National Institutes on Deafness and other Communication Disorders, Caltech's Broad Fellows Program, the Office of Naval Research, and the Max Planck Society.


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-01/ciot-mso012612.php

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Thursday, January 26, 2012

World's most powerful X-ray laser creates 2-million-degree matter

World's most powerful X-ray laser creates 2-million-degree matter [ Back to EurekAlert! ] Public release date: 25-Jan-2012
[ | E-mail | Share Share ]

Contact: Andy Freeberg
afreeberg@slac.stanford.edu
650-926-4359
DOE/SLAC National Accelerator Laboratory

Menlo Park, Calif. -- Researchers working at the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory have used the world's most powerful X-ray laser to create and probe a 2-million-degree piece of matter in a controlled way for the first time. This feat, reported today in Nature, takes scientists a significant step forward in understanding the most extreme matter found in the hearts of stars and giant planets, and could help experiments aimed at recreating the nuclear fusion process that powers the sun.

The experiments were carried out at SLAC's Linac Coherent Light Source (LCLS), whose rapid-fire laser pulses are a billion times brighter than those of any X-ray source before it. Scientists used those pulses to flash-heat a tiny piece of aluminum foil, creating what is known as "hot dense matter," and took the temperature of this solid plasmaabout 2 million degrees Celsius. The whole process took less than a trillionth of a second.

"The LCLS X-ray laser is a truly remarkable machine," said Sam Vinko, a postdoctoral researcher at Oxford University and the paper's lead author. "Making extremely hot, dense matter is important scientifically if we are ultimately to understand the conditions that exist inside stars and at the center of giant planets within our own solar system and beyond."

Scientists have long been able to create plasma from gases and study it with conventional lasers, said co-author Bob Nagler of SLAC, an LCLS instrument scientist. But no tools were available for doing the same at solid densities that cannot be penetrated by conventional laser beams.

"The LCLS, with its ultra-short wavelengths of X-ray laser light, is the first that can penetrate a dense solid and create a uniform patch of plasmain this case a cube one-thousandth of a centimeter on a sideand probe it at the same time," Nagler said.

The resulting measurements, he said, will feed back into theories and computer simulations of how hot, dense matter behaves. This could help scientists analyze and recreate the nuclear fusion process that powers the sun.

"Those 60 hours when we first aimed the LCLS at a solid were the most exciting 60 hours of my entire scientific career," said Justin Wark, leader of the Oxford group. "LCLS is really going to revolutionize the field, in my view."

###

The Oxford-led research team included scientists from U.S. Department of Energy's SLAC, Lawrence Berkeley and Lawrence Livermore national laboratories as well as five other international institutions.

Portions of this research were carried out on the SXR instrument at the LCLS, a division of SLAC National Accelerator Laboratory and an Office of Science user facility operated by Stanford University for the U.S. Department of Energy (DOE). The SXR instrument and the Resonant Coherent Imaging endstation are funded by a consortium whose membership includes the LCLS, Stanford University through the Stanford Institute for Materials & Energy Sciences, Lawrence Berkeley National Laboratory, the University of Hamburg and the Center for Free Electron Laser Science (CFEL). Further support was provided by the UK Engineering and Physical Sciences Research Council, the DOE Basic Energy Sciences contract, the DOE Stewardship Science Academic Alliances program contract, and the German Ministry for Education and Research (BMBF), as well as other grant funding.

SLAC is a multi-program laboratory exploring frontier questions in photon science, astrophysics, particle physics and accelerator research. Located in Menlo Park, California, SLAC is operated by Stanford University for the U.S. Department of Energy Office of Science. To learn more, please visit http://www.slac.stanford.edu.

DOE's Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit http://www.science.energy.gov.



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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


World's most powerful X-ray laser creates 2-million-degree matter [ Back to EurekAlert! ] Public release date: 25-Jan-2012
[ | E-mail | Share Share ]

Contact: Andy Freeberg
afreeberg@slac.stanford.edu
650-926-4359
DOE/SLAC National Accelerator Laboratory

Menlo Park, Calif. -- Researchers working at the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory have used the world's most powerful X-ray laser to create and probe a 2-million-degree piece of matter in a controlled way for the first time. This feat, reported today in Nature, takes scientists a significant step forward in understanding the most extreme matter found in the hearts of stars and giant planets, and could help experiments aimed at recreating the nuclear fusion process that powers the sun.

The experiments were carried out at SLAC's Linac Coherent Light Source (LCLS), whose rapid-fire laser pulses are a billion times brighter than those of any X-ray source before it. Scientists used those pulses to flash-heat a tiny piece of aluminum foil, creating what is known as "hot dense matter," and took the temperature of this solid plasmaabout 2 million degrees Celsius. The whole process took less than a trillionth of a second.

"The LCLS X-ray laser is a truly remarkable machine," said Sam Vinko, a postdoctoral researcher at Oxford University and the paper's lead author. "Making extremely hot, dense matter is important scientifically if we are ultimately to understand the conditions that exist inside stars and at the center of giant planets within our own solar system and beyond."

Scientists have long been able to create plasma from gases and study it with conventional lasers, said co-author Bob Nagler of SLAC, an LCLS instrument scientist. But no tools were available for doing the same at solid densities that cannot be penetrated by conventional laser beams.

"The LCLS, with its ultra-short wavelengths of X-ray laser light, is the first that can penetrate a dense solid and create a uniform patch of plasmain this case a cube one-thousandth of a centimeter on a sideand probe it at the same time," Nagler said.

The resulting measurements, he said, will feed back into theories and computer simulations of how hot, dense matter behaves. This could help scientists analyze and recreate the nuclear fusion process that powers the sun.

"Those 60 hours when we first aimed the LCLS at a solid were the most exciting 60 hours of my entire scientific career," said Justin Wark, leader of the Oxford group. "LCLS is really going to revolutionize the field, in my view."

###

The Oxford-led research team included scientists from U.S. Department of Energy's SLAC, Lawrence Berkeley and Lawrence Livermore national laboratories as well as five other international institutions.

Portions of this research were carried out on the SXR instrument at the LCLS, a division of SLAC National Accelerator Laboratory and an Office of Science user facility operated by Stanford University for the U.S. Department of Energy (DOE). The SXR instrument and the Resonant Coherent Imaging endstation are funded by a consortium whose membership includes the LCLS, Stanford University through the Stanford Institute for Materials & Energy Sciences, Lawrence Berkeley National Laboratory, the University of Hamburg and the Center for Free Electron Laser Science (CFEL). Further support was provided by the UK Engineering and Physical Sciences Research Council, the DOE Basic Energy Sciences contract, the DOE Stewardship Science Academic Alliances program contract, and the German Ministry for Education and Research (BMBF), as well as other grant funding.

SLAC is a multi-program laboratory exploring frontier questions in photon science, astrophysics, particle physics and accelerator research. Located in Menlo Park, California, SLAC is operated by Stanford University for the U.S. Department of Energy Office of Science. To learn more, please visit http://www.slac.stanford.edu.

DOE's Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit http://www.science.energy.gov.



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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-01/dnal-wmp012412.php

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Icy river sweeps girl, 6, away from father

Rick Bowmer / AP

A member of the Multnomah County Sheriff Search and Rescue team searches along the Clackamas River for 6-year-old Vinesa Snegur on Monday.

By msnbc.com staff and news services

ESTACADA, Ore. -- An Oregon man raced along the rain-swollen Clackamas River but couldn't keep up with his 6-year-old daughter who had fallen into the stream and was swept downriver, authorities said.

Rescue workers searched without success Monday for Vinesa Snegur, who fell Sunday into the river,?running fast and cold from a recent winter storm.


The Clackamas County sheriff's office said the search would resume Tuesday.

"It was just a second of inattention," sheriff's Sgt. James Rhodes said of the little girl's fall, explaining that her father turned away, "then splash, and she fell in. He ran and tried to keep up with her, but he was unable to."

Rhodes said the girl and her parents, Igor and Marina Snegur, are from southeast Portland and drove Sunday to play in the snow. They parked near Austin Hot Springs in the Mount Hood National Forest where a road is close to the stream.

The spot is about 60 miles southeast of Portland. There's no cell service, and the family couldn't call for help until they got to a phone at a ranger station an hour later, Rhodes said.

The water temperature Monday was just above freezing, and the river is carrying a heavy load of trees and roots, imperiling rescue workers, he said.

About 50 ground searchers and divers suspended their search at nightfall Monday. A helicopter with thermal imaging equipment also was used to scan the river.

Purple jacket, pink hat
Steve Duin, who joined the search and wrote about it in a column for The Oregonian, said that by noon Monday about 50 people had joined the search, including divers in the water and relatives of the child, who was wearing a purple jacket, pink hat and white pants when she fell.

"Flares have been set out on the road into Austin Hot Springs, the smoke drifting over the divers and the bridge. The black ice is long gone as I slide down the hill, but I slow each time the river comes into view, searching for a blink of purple or pink somewhere," he wrote.

The Oregonian reported that Vinesa's parents were still on the mountain "surrounded by family and trauma specialists" late on Monday.

A series of storms stretching from coast to coast brought snow and ice to the Pacific Northwest, grounded planes in Chicago and 2012's first snow to the Northeast. NBC's Bill Karins and the Weather Channel's Mike Seidel report.

At Vinesa's Mill Park Elementary School, about 140 students visited a special 21-person crisis counseling team Monday, The Oregonian reported. Barbara Kienle, students services director, said half a dozen employees, including some of Vinesa's teachers, also talked to counselors.

"She has many friends," Principal Rolando Florez told the newspaper. "There were lots of sad kids in her class today."

Like many streams in western Oregon, the Clackamas River is swollen by heavy rain that fell late last week as a winter storm moved into the region. The storm caused flooding in many communities in the Willamette Valley.

A mother and her 1-year-old son died after a creek swept away their car from an Albany, Ore., parking lot. A father and his son were able to escape.

Most streams have receded, but more rain is been forecast this week in western Oregon, raising the possibility of more floods.

The Associated Press contributed to this report.

Source: http://usnews.msnbc.msn.com/_news/2012/01/24/10222696-a-second-of-inattention-icy-river-sweeps-girl-6-away-from-father

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Wednesday, January 25, 2012

Fed unlikely to raise rates until at least 2014 (AP)

WASHINGTON ? The Federal Reserve assured consumers and businesses Wednesday that they'll be able to borrow cheaply well into the future.

The Fed said it's unlikely to raise its benchmark interest rate before late 2014, extending its time frame by at least a year and a half. The Fed said record-low rates are still needed to help boost an improving but still sluggish economy.

Stocks, which had traded lower all day, quickly recovered their losses. The Dow Jones industrial average, which had been down about 60 points before the announcement, was up just three points shortly after it.

The central bank has kept its key interest rate at a record low near zero for three years. Later Wednesday, the Fed will release its quarterly economic forecasts. For the first time, those forecasts will show when policy members expect the first increase in the benchmark interest rate.

The Fed said in a statement after its two-day policy meeting that the economy is growing moderately, despite some slowing in global growth. It held off on any other new steps to boost the economy.

The statement was approved on a 9-1 vote. Jeffrey Lacker, president of the Richmond regional Fed bank, dissented, saying he objected to the new time frame for the next rate increase.

The extended timeframe is a shift from the Fed's previous plan to keep the rate low at least until mid-2013. Some economists said the new late-2014 target could lead to further Fed action to try to invigorate the economy.

Fed Chairman Ben Bernanke will discuss the Fed's forecasts and Fed policy at a news conference later.

Beyond the adjusted outlook for interest rates, Wednesday's statement tracked closely to the Fed's previous comments about economic conditions.

The central bank used the same language in describing Europe's debt problems and the impact on the world economy.

The economy is looking a little better, according to recent private and government data. Companies are hiring more, the stock market is rising, factories are busy and more people are buying cars. Even the home market is showing slight gains after three dismal years

Still, the threat of a recession in Europe is likely to drag on the global economy. And another year of weak wage gains in the United States could force consumers to pull back on spending, which would slow growth.

The Fed has taken previous steps to strengthen the economy, including purchases of $2 trillion in government bonds and mortgage-backed securities to try to cut long-term rates and ease borrowing costs.

The idea behind the Fed's two rounds of bond buying was to drive down rates to embolden consumers and businesses to borrow and spend more. Lower yields on bonds also encourage investors to shift money into stocks, which can boost wealth and spur more spending.

Some Fed officials have resisted further bond buying for fear it would raise the risk of high inflation later. And many doubt it would help much since Treasury yields are already near historic lows. But Bernanke and other members have left the door open to further action if they think the economy needs it.

The Fed said it would keep its holdings of Treasury securities and mortgage-backed bonds at record levels and continue a program to further drive long-term rates lower by selling shorter-term securities and buying longer-term bonds.

The Fed announced no further bond buying efforts. But it held out the possibility of doing more. It said it was prepared to adjust its "holdings as appropriate to promote a stronger economic recovery in the context of price stability."

Many economists believe the Fed will launch a third round of bond buying, possibly as soon as its next meeting in March, especially if Europe's debt problems pose a bigger risk to the U.S. economy.

Source: http://us.rd.yahoo.com/dailynews/rss/economy/*http%3A//news.yahoo.com/s/ap/20120125/ap_on_bi_ge/us_federal_reserve

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Georgetown University Medical Center licenses 'theranostic' for development

Georgetown University Medical Center licenses 'theranostic' for development [ Back to EurekAlert! ] Public release date: 24-Jan-2012
[ | E-mail | Share Share ]

Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center

WASHINGTON, D.C. Georgetown University Medical Center (GUMC) has licensed worldwide rights of a potential novel cancer therapy and diagnostic, or "theranostic," to BioMetrx, LLC. The agent was invented by two Georgetown researchers.

GUMC's license agreement with BioMetrx, LLC, a Maryland-headquartered biotechnology company, expedites the translation of the agent, Rasstore, from the laboratory to the clinical setting for further investigation as a potential new therapy.

Rasstore is named for the novel way it could potentially restore the body's natural ability to suppress tumor cells, utilizing the tumor suppressor gene RASSF1A. The agent was invented by Milton Brown, M.D., Ph.D., director of GUMC's Drug Discovery Program, and Partha Banerjee, Ph.D., a world recognized expert on RASSF1A and tumor suppression, also at GUMC.

"It's rewarding for Partha and me to see an agent progress from concept to where we are today on the verge of completing pre-clinical IND enabling studies for a new agent which we believe has applications in prostate cancer and possibly other cancers as well," said Brown, who holds the Edwin H. Richard and Elisabeth Richard von Matsch Endowed Chair in Experimental Therapeutics and is an associate professor at Georgetown Lombardi Comprehensive Cancer Center.

"Rasstore exemplifies the high-quality, early-stage technologies emerging from Georgetown's robust drug discovery program," says Claudia Stewart, vice president of technology commercialization at Georgetown. "Our commercial relationship with BioMetrx represents the process in universities that harnesses the enthusiasm of seasoned entrepreneurs who form a company around the technology, raise funds and then leverage the technical expertise of the inventors to advance the technology...the start up process."

BioMetrx has begun raising the capital required to support clinical investigation.

"We believe Rasstore will be very attractive to other pharmaceutical companies," says John Wells, BioMetrx's Executive Vice President for Global Operations. "This agent has the potential to enhance existing therapeutics because of its potential to restore the body's natural tumor suppression capability."

###

About Georgetown University Office of Technology Commercialization

The Georgetown University Office of Technology Commercialization (OTC) was established in 2002 to advance the University's commitment to protecting its intellectual property and the interests of Georgetown researchers and to strongly engage Georgetown in the economic development of the Washington, DC/Maryland/Virginia area. http://otc.georgetown.edu.

About Georgetown University Medical Center

Georgetown University Medical Center is an internationally recognized academic medical center with a three-part mission of research, teaching and patient care (through MedStar Health). GUMC's mission is carried out with a strong emphasis on public service and a dedication to the Catholic, Jesuit principle of cura personalis -- or "care of the whole person." The Medical Center includes the School of Medicine and the School of Nursing & Health Studies, both nationally ranked; Georgetown Lombardi Comprehensive Cancer Center, designated as a comprehensive cancer center by the National Cancer Institute; and the Biomedical Graduate Research Organization (BGRO), which accounts for the majority of externally funded research at GUMC including a Clinical Translation and Science Award from the National Institutes of Health. In fiscal year 2010-11, GUMC accounted for 85 percent of the university's sponsored research funding.


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Georgetown University Medical Center licenses 'theranostic' for development [ Back to EurekAlert! ] Public release date: 24-Jan-2012
[ | E-mail | Share Share ]

Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center

WASHINGTON, D.C. Georgetown University Medical Center (GUMC) has licensed worldwide rights of a potential novel cancer therapy and diagnostic, or "theranostic," to BioMetrx, LLC. The agent was invented by two Georgetown researchers.

GUMC's license agreement with BioMetrx, LLC, a Maryland-headquartered biotechnology company, expedites the translation of the agent, Rasstore, from the laboratory to the clinical setting for further investigation as a potential new therapy.

Rasstore is named for the novel way it could potentially restore the body's natural ability to suppress tumor cells, utilizing the tumor suppressor gene RASSF1A. The agent was invented by Milton Brown, M.D., Ph.D., director of GUMC's Drug Discovery Program, and Partha Banerjee, Ph.D., a world recognized expert on RASSF1A and tumor suppression, also at GUMC.

"It's rewarding for Partha and me to see an agent progress from concept to where we are today on the verge of completing pre-clinical IND enabling studies for a new agent which we believe has applications in prostate cancer and possibly other cancers as well," said Brown, who holds the Edwin H. Richard and Elisabeth Richard von Matsch Endowed Chair in Experimental Therapeutics and is an associate professor at Georgetown Lombardi Comprehensive Cancer Center.

"Rasstore exemplifies the high-quality, early-stage technologies emerging from Georgetown's robust drug discovery program," says Claudia Stewart, vice president of technology commercialization at Georgetown. "Our commercial relationship with BioMetrx represents the process in universities that harnesses the enthusiasm of seasoned entrepreneurs who form a company around the technology, raise funds and then leverage the technical expertise of the inventors to advance the technology...the start up process."

BioMetrx has begun raising the capital required to support clinical investigation.

"We believe Rasstore will be very attractive to other pharmaceutical companies," says John Wells, BioMetrx's Executive Vice President for Global Operations. "This agent has the potential to enhance existing therapeutics because of its potential to restore the body's natural tumor suppression capability."

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About Georgetown University Office of Technology Commercialization

The Georgetown University Office of Technology Commercialization (OTC) was established in 2002 to advance the University's commitment to protecting its intellectual property and the interests of Georgetown researchers and to strongly engage Georgetown in the economic development of the Washington, DC/Maryland/Virginia area. http://otc.georgetown.edu.

About Georgetown University Medical Center

Georgetown University Medical Center is an internationally recognized academic medical center with a three-part mission of research, teaching and patient care (through MedStar Health). GUMC's mission is carried out with a strong emphasis on public service and a dedication to the Catholic, Jesuit principle of cura personalis -- or "care of the whole person." The Medical Center includes the School of Medicine and the School of Nursing & Health Studies, both nationally ranked; Georgetown Lombardi Comprehensive Cancer Center, designated as a comprehensive cancer center by the National Cancer Institute; and the Biomedical Graduate Research Organization (BGRO), which accounts for the majority of externally funded research at GUMC including a Clinical Translation and Science Award from the National Institutes of Health. In fiscal year 2010-11, GUMC accounted for 85 percent of the university's sponsored research funding.


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Source: http://www.eurekalert.org/pub_releases/2012-01/gumc-gum012312.php

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